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    <ns4:addinfo>Necessary documents for ordering:&lt;ol&gt;&lt;li&gt;Approval form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_6.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_d.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Order form (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_4.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_b.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Category I MTA: MTA for distribution with RIKEN BRC (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_5.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_c.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;li&gt;Acceptance of responsibility for living modified organism (&lt;A HREF="https://mus.brc.riken.jp/ja/wp-content/uploads/form/form_7.docx"&gt;Japanese&lt;/A&gt; / &lt;A HREF="https://mus.brc.riken.jp/en/wp-content/uploads/form/form_g.docx"&gt;English&lt;/A&gt;)&lt;/li&gt;&lt;/ol&gt;&lt;A HREF="https://www.twmu.ac.jp/ILA/" target="_blank"&gt;Lab HP (Japanese)&lt;/A&gt;</ns4:addinfo>
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    <ns1:ESCellLine>E14 [129P2/OlaHsd]</ns1:ESCellLine>
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    <ns1:strainDevelopment xml:lang="ja">開発者／機関：本田浩章先生／広島大学原爆放射線医科学研究所 開発年：2003年</ns1:strainDevelopment>
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    <ns1:strainDevelopment xml:lang="en">Developed by Dr. Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2003.</ns1:strainDevelopment>
    <ns6:brs_depositor xml:lang="en">Hiroaki HONDA</ns6:brs_depositor>
    <skos:altLabel xml:lang="ja">Cas-ex2&lt;+/-&gt;</skos:altLabel>
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    <ns1:colonyMaintenance xml:lang="ja">戻し交配 Background系統名：C57BL/6N（日本チャールズリバー）</ns1:colonyMaintenance>
    <dc:description xml:lang="en">Casp130 (Crk-associated substrate p130) knockout mice.  This mice were generated by the micro-injection of the vector to express Cre recombinase into the eggs of conditional KO strain that have flanked exon 2 encoding SH3 domain of Casp130.  Homozygous mutant mice are embryonic lethal.</dc:description>
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    <ns1:strainDevelopment xml:lang="ja">開発者／機関：本田浩章先生／広島大学原爆放射線医科学研究所開発年：2003年</ns1:strainDevelopment>
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    <ns1:donorDNA>phage P1 loxP site, yeast (Saccharomyces cerevisiae) FRT site, mouse Cas genomic DNA</ns1:donorDNA>
    <ns4:termsAndConditions xml:lang="en">Prior to requesting the BIOLOGICAL RESOURCE, the RECIPIENT must obtain approval from the DEPOSITOR using the Approval Form.</ns4:termsAndConditions>
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    <ns6:brs_depositor xml:lang="ja">本田　浩章</ns6:brs_depositor>
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    <ns1:strainDevelopment xml:lang="en">Developed by Hiroaki Honda, Research Institute for Radiation Biology and Medicine, Hiroshima University in 2003.</ns1:strainDevelopment>
    <ns4:application>FLP/frt system</ns4:application>
    <ns4:application>Cre/loxP system</ns4:application>
    <dc:description xml:lang="ja">Casp130 (Crk-associated substrate p130) 遺伝子のexon2をloxPで挟んだfloxマウス (exon2はSH3 domainをcodeしている) の雌マウスから採卵し、Cre発現ベクターをマイクロインジェクションして得られたCas-ex+/-をヘテロで維持しているマウス。</dc:description>
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    <ns4:termsAndConditions xml:lang="ja">条件を付加する。利用者は提供承諾書を用いて、事前に寄託者の承諾を得る。</ns4:termsAndConditions>
    <ns6:brs_depositorOrganization xml:lang="ja">国立大学法人広島大学</ns6:brs_depositorOrganization>
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    <ns4:application>Cell Biology Research</ns4:application>
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    <ns1:colonyMaintenance xml:lang="ja">戻し交配Background系統名：C57BL/6N（日本チャールズリバー）</ns1:colonyMaintenance>
    <ns1:expectedDelivery xml:lang="en">C (3-6 months)</ns1:expectedDelivery>
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